동물실험 대체법 : 피부 부식성 시험 대체 : Corrositex

CORROSITEX

 

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What is Corrositex?                      

 

물질의 피부 부식성 검사 및 위험물의 UN Packing group I, II, III 분류

 

( 동물을 이용하지 않고 ( 동물실험을 하지않고 ) 화장품 생활용품 각종 화학물질의

  

   피부 부식성검사 )

 

( 화학 물질 등의 해상 및 항공 운송을 위한 위험 물질 등급 분류 )

 

Corrositex is an invitro test that determines chemical corrosivity and permits assignment of Packing Group classification for Class 8 corrosives. This test replaces the rabbit test of dermal corrosivity by providing a reliable means of mimicking this test. The proprietary core technology of the Corrositex test is based upon a biomembrane and chemical detection system, which becomes colored when exposed to potentially corrosive substances.

Why Use Corrositex?

Because it will save you time and money.

• Time Savings: Unlike animal testing that can take 2 to 4 weeks, Corrositex testing can provide a Packing Group determination in as little as 3 minutes and no longer than 4 hours.
• Cost Savings: In a recent evaluation, one customer saved up to $50,000 annually, in shipping costs, for a single compound when using the Corrositex test to define the Packing Group instead of relying on pH. In addition to the reduction in shipping charges, additional cost savings are found in the areas of workplace safety and MSDS development.

 

Regulatory Acceptance. Following is a list of agencies that accept Corrositex. This list continues to grow as regulatory bodies look for more accurate, cost-effective and humane testing methods. Copies provided upon request.

 

Department of Transportation - DOT-E 10904

Original exemption granted April 28, 1993

Renewals granted:

March 22, 1995
November 30, 1997
January 12, 1999
December 12, 2000
September 20, 2002
July 19, 2004

 

Consumer Product Safety Commission (CPSC)

Formal Acceptance, NIEHS press release dated 3/21/00

 

European Centre for the Validation of Alternative Methods (ECVAM)

12/2002

 

EPA Federal Register / Vol. 60, No. 142 Dermal Corrosion

Method 1120       June 13, 1997

Formal Acceptance, NIEHS press release dated 3/21/00

 

Food & Drug Administration (FDA)

Formal Acceptance, NIEHS press release dated 3/21/00

 

International Air Transportation Association (IATA)

Letter of acceptance dated December 17, 1993

 

National Institute of Environmental Health Sciences (NIEHS)

Endorsement dated 6/22/99

 

Occupational Safety and Health Administration (OSHA)

Letter of Interpretation dated March 3, 1994

Formal Acceptance, NIEHS press release dated 3/21/00

 

Transport Canada - Permit For Equivalent Level of Safety SU 4483

Original approval 8/14/96

Additional renewal 9/18/98

Additional renewal 1/15/01
Full Draize Replacement Acceptance 3/5/02

 

How the Test Works

 

The Corrositex testing system consists of a glass vial filled with a chemical detection fluid capped by a proprietary bio-barrier membrane, which is designed to mimic the effect of corrosives on living skin.
As soon as the corrosive sample destroys this bio-barrier, the fluid below changes color or texture. Users simply record the time it takes for the sample to break through the membrane. Then, depending on their needs, they can assign the proper U.N. Packing Group classification for U.S. DOT or EPA compliance, or use the data as a ranking tool or to substantiate marketing claims.

 
 

다일과학교역

 

www.Lab365.co.kr