다일과학교역

MatTek Life Sciences, a subsidiary of CELLINK, today announced the acceptance of the EpiDerm™ Phototoxicity Test as part of Test Guideline No. 498 In vitro Phototoxicity: Reconstructed Human Epidermis Phototoxicity Test Method by the Organization of Economic Cooperation and Development (OECD). This effort is very much in line with the Group’s goals to reduce and eventually replace animal testing..

MatTek's EpiAirway tissue model of the human bronchial airway is a reliable, non-animal method for toxicology testing. Human Relevance in vitro EpiAirway is biologically active, lab-grown human bronchial tissue that features mucus-producing cells and beating cilia. Diverse Donor Inventory EpiAirway has a catalog of 30+ donors with patient information and histories, including diseased donors with..

MatTek's EpiAirway MicroTissue system is the optimal platform for testing toxicity of the lungs and bronchial airway in vitro. EpiAirway is used to determine the concentration required to reduce tissue viability to 75% of vehicle control-treated tissues (IC-75) of a test chemical. This value can then be used to predict GHS or EPA classification. Coming Soon: EpiAlveolar ​ An ..

Drug–Drug Interaction and Synergy of IL-17 and IFN-γ in the Induction of Inflammatory Responses in 3D Human Small Intestinal Tissue Model Seyoum Ayehunie1, Zachary Stevens1, Timothy Landry1, Jon Gilbert2, Alex Armento1, Mitchell Klausner1, and Patrick Hayden1 1 MatTek Corporation, Ashland, MA, USA, United States 2Cyprotex, Watertown, MA - USA Poster #R6356 Thursday Con..

Rhinovirus Infection in EpiAirway Immunofluorescence micrographs of transverse sections of EpiAirway shows RV-A16 replication. Positive immunofluorescence staining for mabj2 (green) was not observed in uninfected control tissues (top panel), but was observed in RV-A16 infected tissues (bottom panel); DAPI staining in blue shows cell nuclei. (Green in top panel is autofluoresce..

EpiIntestinal ( 3D human in vitro intestine model ) ​ ​ View Applications Pages: Intestinal Inflammation Intestinal Drug Permeation Intestinal Fibrosis Intestinal Epithelial Restitution Request the EpiIntestinal Data Sheet & Ordering Information ​ ​------------------------------------------ Advancing your 2D research into the the 3D world Drug Discovery..

EpiCorneal A New 3D in vitro corneal tissue model MatTek’s EpiCorneal ocular tissue model consists of normal human Corneal epithelial cells which have been cultured to form a stratified, squamous epithelium that closely parallels normal human corneal tissue. EpiCorneal provides a unique platform for ocular drug screening, infection and corneal inflammation testing. Ideal for..

Organotypic 3D Human Small Intestinal Tissue Model Figure 1: Schematic representation of the SI tissue model. SI epithelial cells are seeded onto a collagenfibroblast gel in cell culture inserts and air-lifted so that the apical tissue surface is exposed to the atmosphere. The tissue is fed by medium diffusing through the microporous membrane on the bottom of the cell culture ..

In Vitro Human Alveolar Tissue Model for Inhaled Drug Delivery Applications Figure 1: Schematic illustration of air/liquid interface (ALI) culture on microporous membrane inserts. Because the apical tissue surface is not submerged in culture medium, test articles and other exogenous stimuli (e.g.chemicals, virus, bacteria, aerosoles, etc.) can be topically applied, as occurs i..

Skin Lightening The Model MatTek's MelanoDerm™ System consists of normal, human-derived epidermal keratinocytes (NHEK) and melanocytes (NHM) which have been cultured to form a multilayered, highly differentiated model of the human epidermis. The NHM within co-cultures undergo spontaneous melanogenesis leading to tissues of varying levels of pigmentation. The tissues are prod..