Commercial Launch of EpiOcularTM Tissue Production in Europe

 

Commercial Launch of EpiOcular^TM Tissue Production in Europe

 

www.mattek.co.kr

 

ASHLAND, Mass. (June 27, 2013) – MatTek Corporation, Ashland, MA, (USA) announced today that MatTek In Vitro Life Science Laboratories (IVLSL), located in Bratislava, Slovakia, will begin producing EpiOcular for commercial sale on July 1.

The EpiOcular tissue model is produced under GMP conditions and tissues produced in Bratislava and MatTek’s U.S. facilities meet the same quality control specifications, as confirmed by a successful audit by MatTek’s Quality Assurance department.

Increasing the availability of EpiOcular in Europe will not only provide customers with greater ease of ordering and lower shipping costs, but will also aid customers in meeting the requirements of the 7^th Amendment to the Cosmetics Directive and REACH guidelines.

"The reconstructed human cornea-like EpiOcular tissues can be used for in vitro assessment of eye irritation potential of substances and formulations,” said Dr. Helena Kandarova, Director of MatTek IVLSL. “Moreover, the EpiOcular Eye Irritation Test has been pre-validated by COLIPA, now Cosmetics Europe, and is in the final stages of a validation process driven by Cosmetics Europe and ECVAM,” she said.

Since establishment, IVLSL has provided European customers with shorter transit times, fewer customs delays and lower shipping costs. The IVLSL facility began producing EpiDerm for commercial sale in January of 2012.

“We look forward to better servicing our European customers directly from our new state-of-the-art tissue production facility in Bratislava,” said Mitchell Klausner, President and CEO of MatTek Corporation. Mr. Klausner added, “The ability to ship both EpiOcular and EpiDerm tissues from within the EU will further assist companies in eliminating unnecessary animal use for determining ocular and dermal irritation.”

About MatTek – MatTek Corp. is the world’s largest independent producer of in vitro human epithelial tissue equivalents. With 20 years of publicly available QC data and over 700 technical references supporting our claim of “Unsurpassed Long-Term Tissue Reproducibility”, MatTek human tissue equivalents are used in product development, claims substantiation (over 400 patent references cite the use of MatTek tissues), safety assessment, and drug discovery/development in many industries including Cosmetics, Personal Care, Household Products, Chemicals, Pharmaceuticals and Biotech.

 

Contact Information in Korea:

 

(주)다일과학교역

E: Skin@mattek.co.kr
T: 02-887-3116
F: 02-337-3742
W: www.mattek.co.kr

 

 

 

EpiOcular

Normal Human 3D (NHu-3D)

in vitro Corneal Tissue Model

Ocular Irritation Testing...Without the Use of Animals!

 

 

 

 

Applications

• Ultra-Mildness Testing
• Hazard Identification
• Risk Assessment

 

Ultra-Mildness Testing

The EpiOcular Ultra-Mildness assay is routinely utilized for assessing ultra-mild cosmetics and personal care products for which the rabbit Draize test is insensitive. The economic advantages of this assay are significant since large clinical panels would be necessary to distinguish differences between extremely mild formulations. For any product for which mildness is important...the EpiOcular Ultra-Mildness Test is a must! Learn more here.

Ideal for:

Eye-care Cosmetics

Personal Care Products

Facial Cosmetics

 

Hazard Identification

The EpiOcular Eye Irritation Test (EIT) provides numerous chemical, cosmetic and personal care companies with an important in vitro screening tool for addressing regulatory or consumer safety issues related to their products. The EIT has been pre-validated and is currently part of an ECVAM validation study to replace animal-based ocular irritation testing. A formal validation announcement is anticipated in the near future! Learn more here.

Ideal for:

Cosmetics & Personal Care Products

Household Products

Organic and Inorganic Raw Materials

 

Risk Assessment

Developed as an alternative to the rabbit Draize test, the EpiOcular ET-50 assay reproducibly and consistently predicts Draize scores of surfactants and surfactant-based formulations over a broad range of ocular irritation potentials. Learn more here.

Ideal for:

Surfactant-based Products

Shampoos

Cleaners

Body washes, etc.

Surfactant-based Formulations

 

EpiOcular Characteristics

EpiOcular is cultured using non-transformed, primary human epithelial cells. EpiOcular assays utilize objective endpoints and end users typically attain extremely high levels of reproducibility (e.g. coefficients of variation <10%). EpiOcular's highly accurate predictive capacity and its low variability are hallmarks of the tissue model. Other EpiOcular characteristics include:

• 3D Model of Human Corneal Epithelium
• Normal, Human Cells
• Highly Differentiated, Ready-To-Use
• Mitotically and Metabolically Active
• Compatible with Water Soluble/Insoluble Materials
• 15 Years of Publicly Available QC Data
• Cost Effective Alternative to Animal Testing or Human Clinical Testing

Find out more about EpiOcular here!

 

 

Discovery, Development, Delivery & Toxicology Tools

Standardized Human 3D in vitro Tissue Models